Pharmacokinetics and Pharmacodynamics

Pharmacokinetics and Pharmacodynamics parameters become important because of the association between host drug concentrations, microorganism eradication, and resistance. The Pharmaceutical industry's long successful strategy of placing big bets on a few molecules, promoting them heavily and turning them into blockbusters worked well for many years, but its R&D productivity has now plummeted and the environment’s changing. Drug biotransformation reactions. Pharmacokinetics influences decisions over the route of administration. For drugs to produce their effects they must interact with the body. This can happen in many ways and depends on the properties of the drug, and will be discussed later in this chapter. Pharmacokinetics influences decisions over the route of administration. The processes that occur after drug administration can be broken down into four distinct areas (known as ADME) Absorption of the drug, Distribution of the drug molecules, Metabolism of the parent drug and Excretion or elimination of the drug and its metabolites.

 

  • Track 1-1 Pharmacokinetic models
  • Track 2-2 Bioavailability
  • Track 3-3 Clinical pharmacokinetics
  • Track 4-4 Population pharmacokinetics
  • Track 5-5 Multicellular pharmacodynamics
  • Track 6-6 Toxicodynamics
  • Track 7-7 Pharmacokinetic aspects
  • Track 8-8 Drug interactions and pharmacological compatibilities
  • Track 9-9 Receptor theory for drug effects
  • Track 10-10 Clinical efficacy and safety evaluation
  • Track 11-11 Novel options for the pharmacological treatment of chronic diseases
  • Track 12-12 Drug biotransformation reactions

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