Immunopharmacology is that area of pharmacological sciences dealing with the selective variation of specific immune responses and, in particular, of immune cell subsets. The first generation of immune-modulating agents included molecules drawn from oncology. The second generation, notably cyclosporine, exploited some natural agents able to block several signal transduction pathways. To deal with the expanding field of immunopharmacology, some limitations are required. However, in recent years, the advances about how the immune system works have identified several molecular targets suitable for more selective modulation of immune function. These targets can be broadly divided into surface molecules and soluble mediators. Surface molecules play a fundamental role in antigen recognition, immune response activation, homing and effector functions. Soluble mediators are involved in lymphocyte proliferation and differentiation, inflammatory response and cell recruitment.
- Track 1-1 Autoimmunity & autoimmune disorders
- Track 2-2 Immunotoxicology
- Track 3-3 Innate Immunity
- Track 4-4 Immunopathology
- Track 5-5 Immunotherapy